Mat's body is a lot smarter than he is. After two weeks of nausea and hospital visits for hydration, Mat showed up at MGH for clinical trial week #5. He swallowed his dose of AV-412 (the catchy name for the chemo) ... and promptly threw up. Since the drug didn't "stick," he got an impromptu vacation from chemo for the week.
That combined with the two prior weeks of misery convinced his doctor to get an early CT scan to see if it was worth it to continue this fun-fest. The scan results showed that the cancer hasn't growth in the last four weeks, which is pretty good for being on the chemo such a short time.
Mat was able to spend the rest of his chemo vacation week resting, and week #6 has gone better. Despite being on six (count 'em) different drugs to control nausea, chemo day (Monday) was every bit as miserable as all the other chemo days. The improvement was on Tuesday, when he spent a day at MGH getting IV fluids and sleeping to make up for the day before. Mat was also scheduled for fluids on Thursday, but felt well enough to skip that appointment.
We do spend a lot of time thinking about the trade-off of quality of life for quantity of life, and have been very close to throwing in the towel on AV-412 several times in the last few weeks. But if the misery is mostly confined to Monday and Tuesday, well, it's still not a picnic in the park, but maybe we can have a little quality and quantity.
Some people are so hard to please.